We are an interdisciplinary research lab with a broad scientific focus on quantitative and computational biology, core domain knowledge in immune repertoires and evolutionary dynamics, and technical expertise in scientific computing, mathematical and biophysical modeling, and machine learning. We aim to cultivate an inclusive and collaborative environment where all lab members are conversant in theory, computation, and experiment.
Latest lab news → View All
2025
Preprint: BH Schlomann, WS DeWitt, Y Zhang, K Shah. Ignition criteria for trigger waves in cell signaling.
arXiv:2508.16810
[q-bio.CB] Read more
Evo-Hub receives funding from the Simpson Center for the Humanities for 2025-2026! Read more
Charles Bennington has been working with us this summer via the UW School of Medicine—Gonzaga University Summer Research Program. Read more
Two collaborative preprints investigate how fitness of affinity-maturing B cells depends on affinity changes in their mutating B-cell receptors, both using B-cell lineage trees from our recent GC (germinal center) replay preprint Read more
Forward-Time Equivalent of a “Retrocausal” Diffusion Hidden Variable Model for Quantum Mechanics, arXiv:2507.13593
[quant-ph].
Will is off to Stockholm for the Nordic Institute for Theoretical Physics (Nordita) workshop: Eco-Evolutionary Processes in Context: a Statistical Physics Approach (July 14–25, 2025). Read more
Postdoc Maggie Russell receives the UW Distinguished Dissertation Award for her PhD work Inferring mechanisms of V(D)J recombination using statistical inference on high-throughput immune repertoire data.
Charles Bennington (Gonzaga University Computer Science major) joins the lab for a summer internship via the UW School of Medicine—Gonzaga University Summer Research Program. Read more
Replaying germinal center evolution on a quantified affinity landscape. bioRxiv
Will and Maggie attend Evo-WIBO in Blaine, WA (April 4–6, 2025).
MolES PhD student Arnav Nagle joins for a rotation, co-advised with Armita Nourmohammad. Read more
The lab welcomes its first two members today!
Dr. Magdalena (Maggie) Russell joins as a postdoc, and Carlo Melendez joins as a GS rotation student for the Spring quarter. Read more
2024
Off to Santa Fe Institute for Evolutionary dynamics of cheating in viral infections II (November 3–8, 2024). Read more
Will is in residence at Kavli Institute for Theoretical Physics (KITP) for Interactions and Co-evolution between Viruses and Immune Systems (September 24 – October 11, 2024). Read more
The DeWitt lab opens in the Foege building at University of Washington’s Department of Genome Sciences! Read more
Mean-field interacting multi-type birth–death processes with a view to applications in phylodynamics in Theoretical Population Biology, Volume 159.
Off to Santa Fe Institute for Evolutionary dynamics of cheating in viral infections (April 10–15, 2024). Read more
2023
Off to Santa Fe Institute for Slow-fast dynamics in biological systems II (October 7–11, 2023).
Off to Aspen Center for Physics to attend the Program on statistical physics & adaptive immunity (August 14–25, 2023). Read more
